Synthase Vs Synthetase enzyme

SynthaseSynthatase
Catalyzes the formation of new chemical bond between substrates without using ATPCatalyze the formation of a new chemical bond between substrates using ATP
Does not require ATP for the bond formation reactionRequires ATP as a source of energy for the bond formation
Can perform both ligation and cleavage reactionPrimarily involved in ligation reaction forming new chemical bond
Uses substrates directly to form the productsRequires ATP to activate one or more substrates, which are then used to form the products
Examples. Citrate synthase, acetyl CoA synthaseExamples. Aminoacyl-tRNA synthetase, glutamine synthetase

Lyases Vs Ligase enzymes

Lyases EnzymeLigases Enzyme
These enzymes catalyze bond breaking reactionThese enzymes catalyze bond formation reaction.
Acts on single substrate per reactionActs on two substrate or reactant per reaction
Elimination reactions are catalyzed by LyasesHydrolysis reaction are catalyzed by Ligases
Double bond is formedChemical bond is formed
In Glycolysis and Krebs cycle, lyases are usedLigases are used in the DNA replication process
Lyases are also known as synthasesLigases are also known as synthetases

Phosphatase Vs Phosphorylase Enzyme

PhosphatasePhosphorylase
It catalyze the removal of phosphate group from moleculesIt catalyze the addition of phosphate group to the molecules
It brings about dephosphorylationIt brings about phosphorylation
Substrates are various like proteins, nucleotidessubstrate is Glucose-1-phosphate
Examples, protein phosphatase, acid phosphataseexample.. Glycogen phosphorylase

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  1. seo experts December 21, 2024

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